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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC24A2
All Species:
12.42
Human Site:
S427
Identified Species:
22.78
UniProt:
Q9UI40
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UI40
NP_065077.1
661
73664
S427
T
D
V
E
M
T
P
S
S
D
A
S
E
P
V
Chimpanzee
Pan troglodytes
XP_528551
661
73638
S427
T
D
V
E
M
T
P
S
S
D
A
S
E
P
V
Rhesus Macaque
Macaca mulatta
XP_001108751
661
73840
S427
T
D
V
E
M
T
P
S
S
D
A
S
E
P
V
Dog
Lupus familis
XP_852036
664
74187
A430
E
M
T
T
P
S
D
A
S
E
P
V
Q
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CGQ8
605
66848
Q381
Q
E
Q
Q
P
P
P
Q
P
P
P
P
E
P
E
Rat
Rattus norvegicus
O54701
670
74638
S436
M
T
P
S
S
E
A
S
E
P
V
Q
N
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514353
346
38802
Q123
P
K
D
L
F
S
L
Q
E
R
R
R
G
A
V
Chicken
Gallus gallus
Q9IAL7
651
72677
E417
H
E
K
G
A
K
V
E
V
A
V
T
P
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q49SH1
513
56764
S289
F
Q
D
D
S
G
Y
S
H
L
S
L
S
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6A0
888
95868
I657
S
A
A
N
H
V
K
I
N
L
K
E
T
T
L
Honey Bee
Apis mellifera
XP_396230
658
71609
S427
T
S
T
A
A
H
Y
S
G
A
S
S
K
E
T
Nematode Worm
Caenorhab. elegans
NP_001040663
596
66359
I373
R
S
S
Q
I
E
E
I
K
S
L
L
E
E
Q
Sea Urchin
Strong. purpuratus
XP_787540
651
70927
T417
D
H
Q
F
E
K
S
T
E
Q
L
T
T
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.1
93.2
N.A.
35.2
88.6
N.A.
39.3
77
N.A.
31
N.A.
38.9
46.9
42.2
39.4
Protein Similarity:
100
99.8
98.6
95.3
N.A.
53.5
93.4
N.A.
44.9
86.8
N.A.
50.3
N.A.
53.2
61.2
60.3
53.8
P-Site Identity:
100
100
100
6.6
N.A.
20
6.6
N.A.
6.6
6.6
N.A.
6.6
N.A.
0
20
6.6
0
P-Site Similarity:
100
100
100
33.3
N.A.
33.3
6.6
N.A.
13.3
20
N.A.
20
N.A.
20
33.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
16
0
8
8
0
16
24
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
24
16
8
0
0
8
0
0
24
0
0
0
0
0
% D
% Glu:
8
16
0
24
8
16
8
8
24
8
0
8
39
16
8
% E
% Phe:
8
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
8
0
0
8
0
0
0
8
8
16
% G
% His:
8
8
0
0
8
8
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
8
0
0
16
0
0
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
16
8
0
8
0
8
0
8
0
0
% K
% Leu:
0
0
0
8
0
0
8
0
0
16
16
16
0
8
8
% L
% Met:
8
8
0
0
24
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
0
0
0
8
8
8
% N
% Pro:
8
0
8
0
16
8
31
0
8
16
16
8
8
39
0
% P
% Gln:
8
8
16
16
0
0
0
16
0
8
0
8
8
0
8
% Q
% Arg:
8
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% R
% Ser:
8
16
8
8
16
16
8
47
31
8
16
31
8
0
8
% S
% Thr:
31
8
16
8
0
24
0
8
0
0
0
16
16
8
8
% T
% Val:
0
0
24
0
0
8
8
0
8
0
16
8
0
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _